User blog comment:Omega natsu2/Chapter 413: The Book of E.N.D., Predictions./@comment-5303512-20141216185028/@comment-7418318-20141216194301

It probably only means that Mard thinks that Humans are helpless against Demons without magic.

And he's probably right too. Even the Demon Gates like Jackal, Torafuse & Co are as good as impossible to defeat without magic or magical items and E.N.D. is supposed to be a few magnitudes stronger still.