User blog comment:IamJakuhoRaikoben/Chapter 366: 1000 Souls, Review./@comment-24016459-20140110153936/@comment-4829046-20140111141006

"Actually the only anime I ever saw that has realistic body- and face proportions is Jin-Roh."

Actually, I can name several more but even they aren't really realistic per se. Sometimes the characters are really toned and drawn in an attractive manner. You don't really see how a "not-so-attractive" young girl looks like in general. They all have good figures most of the time. Heck, even Risley had a slim version.... and its a joke in manga for a fat girl to become a surprising bishoujo after some dieting.

Some of the Studio Ghibli films however don't have that comedic facial animation. Their eyes remain the same. The mouths however do have a big gape but that's not for comedy purposes, just the art-style.