User blog comment:Ncduru/The Erza-Irene Connection/@comment-207.45.155.253-20160425130814/@comment-7418318-20160425133911

Sama can mean Lady or Lord, but can have other meanings too, including "honoured ", which I'd even go so far to call the most accurate translation.

I'm not aware of any connection between -sama and age. As far as I know even children can be called -sama, though the situations where it's fitting are few and far between (outside of games and sarcasm anyway :P ).